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New Applications of Green Fluorescent Protein in Tumor In Vivo Optical Imaging
QIAN Ai-ping,HUA Guo-ran,DAI Li-juan(School of Mechanical Engineering,Nantong University,Nantong 226019,China)The luminescence mechanism and basic properties of green fluorescent protein,the mechanism of in vivo molecular imaging are reviewed first.The latest applications of the green fluorescent protein in the metastasis mecha-nism,angiogenesis,drug filtration and efficacy judgment of tumor in optical imaging technology are analyzed.As a new reporter gene of in vivo molecular imaging technology,green fluorescent protein(GFP) plays an important role in the researches of early diagnosis,timely and non-invasive monitoring of tumor development,and treatment efficacy.Fi-nally,the future prospect of in vivo molecular imaging technologies is given.
Reading and Voxelization of 3D Models
XIE Xiang-rong,XU Hai-li(School of Mechanical Engineering,Nantong University,Nantong 226019,China)The file format and reading method of 3DS models are introduced.The material and the coordinates of vertex、edge、face of the 3DS model are read by using the OpenGL library functions in VC++.And a voxelization algorithm based on edclidean distance is adopted to convert 3D polygon mesh models to accurate 6-adjucent or 26-adjucent voxel models,which is helpful for the regularization of 3D models and is convenient to acquire external properties of 3D models.By using OpenGL,the reading and redrawing of 3D voxel models can be performed.Experiment results indicate that the algorithm is efficient and effective to produce voxelized models.
Research Status of PumpHydraulic Design Methods
SHI Weidong;ZHANG Yue;XIAO Yu;ZHOU Ling;School of Mechanical Engineering, Nantong University;National Research Center of Pumps, Jiangsu University;Pump is the core power source of the fluid conveying system. It has been a research focus in the field of fluid machinery to carry out the optimal design of pump and realize energy saving and consumption reduction. In recent years, many scholars at home and abroad have carried out systematic and in-depth research on the pump optimization design technology, and accumulated abundant practical experience in the design of the impeller, guide vane and volute of the pump individually or as a whole. This paper reviews the methods of hydraulic design based on the theory of one, two and three elements, summarizes the advantages and disadvantages of each optimization method, summarizes the recent research and leading methods for the hydraulic design of impeller, guide vane and volute in recent years, and lays a foundation for the development of pump design methods in the future. The design method of numerical simulation combined with threedimensional theory and optimization algorithm has become the mainstream means of pump optimization design. It can be expected that with the improvement of computing power of large-scale computer and the development of optimization algorithm, the level of hydraulic design of pump will be greatly improved and the overall technical progress of pump industry will be promoted.
Overview of digital twin education applications: historical origins,current existence, and future challenges
QIAN Xiaolong;LI Fengyun;SHI Wenya;HUANG Beibei;In the digital age, the rise of digital twin has brought unprecedented opportunities and challenges to the educational field. Therefore, how to promote the application of digital twin in the education sector has become an urgent problem to be solved. Based on the reality, this research conducts an in-depth analysis of the "past life", "present life" and "future" of the application of digital twin in educational field, so as to reveal its historical origin,realistic existence, future challenges as well as coping strategies. The research finds that: The application of digital twins in education was first enlightened by the technological breakthrough of the aviation industry, further developed in the conceptual prototype of artificial intelligence, and eventually applied to educational field. Digital twin has significant technical advantages in the application of educational field now. Meanwhile, its correlative infrastructures are gradually developing, and its application fields are also changing rapidly. However, there are still some inevitable challenges like technical bottlenecks, ethical norms, tremendous equipment costs, application paradigms, etc. Therefore,in the future, it is necessary to effectively play the educational value of digital twin from the aspects of government,society, and individuals in order to further deepen and expand its scope and value of educational application.
Stability Analysis on a Class of SIQR Epidemic Dynamical Model with Vaccination and Isolated Items
GUO Xiao-jun LI Da-zhi (School of Sciences,Nantong University,Nantong 226007,China)In this paper,we analyze a class of epidemic dynamical model with lifelong immunity which includes vac- cination and isolation.The threshold data Rq is obtained,which determines the existence of an infectious disease.When Rq≤1,there only exists disease-free equilibrium E0,which is globally and asymptotically stable.When Rq>1,there ex- ist two equilibrium points,the disease-free equilibrium Eo which is unstable and the endemic equilibrium E* which is globally and asymptotically stable.Through mathematic software MATLAB,the SIQR model can also be numerically simulated,showing that the effect of combining vaccination and quarantine is conspicuous.
Single-Molecule Magnets and Materials of Molecular Spintronics
JIANG Guo-min,CHEN Ting-ting,SHI Chuan-guo,JIANG Guo-qing,SHI Yu-jun(School of Chemistry and Chemical Engneering,Nantong University,Nantong 226007,China)The recent achievements in the preparation,structure,properties and applications of molecular spin-transistor and molecular spin-valve are briefly introduced.Single-molecule magnets(SMMs) consist of an inner magnetic core with a surrounding shell of organic ligands.The physical and chemical properties of SMMs could be improved by modi-fying the structure of organic ligands and exchange the magnetic ions.[Co(Tpy-(CH2)5-SH)2] mononuclear magnet molecule with alkyl spacers permits transportation in the weakly coupled regime,and [Co(TerPy)2] without spacers show strong coupling to the electrodes,with exceptional high kondo temperatures of around 25 K.Some interesting physical effects emerged when divanadium([(N,N′,N″-trimethyl-1,4,7-triazacyclononane)2 V2(CN)4(μ-C4N4)]) was directly grafted to the electrodes.
Study of Denim Fabric Dip Dyeing Process with Indigoid Dyes
YANG Jing-xin, WANG Hai-feng, LI Cheng-xuan, YU Wen-lin (School of Chemistry and Chemical Engineering, Nantong University, Nantong 226007, China)In this article, the process of dip dyeing of denim fabric with indigoid dyes was introduced. The factors such as temperature, concentration, dyeing time, oxidizing time and times of dyeing and oxidizing were discussed. The preferred dyeing process was confirmed by analyzing and comparing the K/S value of dyed cotton yarn with indigoid dyes.
Research progress of electrocatalytic reduction of nitric acid to synthesis of ammonia in aqueous electrolyte
XIAO Kaiwen;ZHANG Chi;TAO Zhangyi;GE Ming;YUAN XiaoleiAmmonia(NH3) is not only the main component of nitrogen fertilizers but also serves as a high-energy-density carbon-free hydrogen storage medium, making it an important chemical substance in modern industry. Currently, industrial NH3 synthesis is still dominated by the traditional Haber-Bosch process. This process operates under high temperature and high-pressure conditions, consuming large amounts of fossil fuels and releasing large amounts of carbon dioxide. In recent years, an increasing number of researchers have focused on electrochemical nitrogen reduction reaction(NRR) technology for NH3 synthesis driven by renewable energy. However, due to the high dissociation energy of the N≡N bond and the low solubility of N2, the yield and Faradaic efficiency of electrochemical NRR are relatively low. Nitrate(NO3~-) is a common nitrogen-containing pollutant. Because NO3~-has high solubility and the N=O bond has low dissociation energy, it can serve as an ideal raw material for NH3 production. Starting from the mechanism of electrocatalytic nitrate reduction reaction(NO3 RR), this review systematically introduces the current research status of NO3 RR electrocatalysts and discusses various strategies for developing nitrate reduction catalysts. Finally, the challenges and prospects of electrocatalytic NO3~-reduction technology are summarized to promote future green and sustainable large-scale NH3 synthesis.
Research Progress of Influence Factor of Cationic Antibacterial Polymers
GUO Jiangna;SHI Jie;WANG Mengyao;MAO Hailei;YAN Feng;Bacterial infections seriously threatens human health which has become a global problem, while the emergence of drug-resistant bacteria and the gradual increase of drug resistance have exacerbated this problem.Therefore, antibacterial materials or antibiotics with high antibacterial efficiency and low toxicity and without drug resistance are urgently needed. Cationic polymers with cationic groups in the structures enjoy special physicochemical properties, which have attracted wide academic attention. The cationic groups in the cationic polymers can electro statically bind to the electro-negative bacterial cell membrane, simultaneously the hydrophobic chains of cationic polymers can insert into the phospholipid bilayer of the cell membranes, disturbing the cell membranes, which leads to the bacteria′s death. Moreover, the structural designability of cationic polymers makes it possible to obtain antibacterial materials with adjustable antibacterial properties by adjusting its cationic and anionic structure and composition. This study mainly summarized the influence of cationic structure, anionic structure, hydrophobic chain, electric density and functional groups on cationic antibacterial polymers, it reveals that adjusting its cationic structure makes antibacterial properties adjustable.
The Latest Advance of TMS320C6000 DSPs
CHEN Jian-ping,WU Guo-qing(Nantong University,Nantong 226007,China)The technology of digital signal processors presented by the TI's TMS320 family of DSPs has been developed rapidly in recent years.New chips and new technology arise almost every year.Among the many DSP products manufactured by TI,TMS320C6000 series are the most powerful,representing the top level of today's DSP technology.After giving a brief introduction of the basic features of TMS320C6000 DSPs,this article lays stress on introducing the latest advance of TMS320C6000 series in recent two years,including TMS320C62x?TMS320C67x?TMS320C64x and TMS320DM64x.